# The effectiveness of specialist cognitive behavioural therapy for functional neurological disorder: a service evaluation

**Authors:** Rhiannon White, Susannah Pick, Trudie Chalder

PMC · DOI: 10.3389/fpsyt.2026.1786295 · Frontiers in Psychiatry · 2026-03-13

## TL;DR

Specialist cognitive behavioral therapy for functional neurological disorder improves psychological and functional outcomes in real-world clinical settings.

## Contribution

Demonstrates effectiveness of specialist CBT for FND in routine clinical practice using real-world data.

## Key findings

- Significant improvements in psychological distress and functional impairment were observed during CBT.
- Five of six cognitive-behavioral response domains showed improvement across treatment.
- No significant changes were found in physical functioning or pain measures.

## Abstract

Functional neurological disorder (FND) is a common and disabling condition associated with high levels of functional impairment and psychological distress. Psychological therapies such as cognitive behavioural therapy (CBT) are increasingly recommended as part of multidisciplinary care, but evidence from real-world clinical settings remains limited.

This retrospective observational cohort study evaluated outcomes from a specialist CBT programme for adults with FND using routinely collected clinical data. Self-report measures of depression, anxiety, psychological distress, functional impairment, physical functioning, pain, and six cognitive-behavioural responses were collected before, during, and at the end of treatment. Linear mixed-effects models were used to examine change over time, with correction for multiple testing.

Data from 234 patients were analyzed (70.5% female; mean age 40.9 years). Despite low completion of measures at follow up, significant improvements were observed in psychological distress, functional impairment, and five of the six cognitive-behavioural response domains across treatment, whereas no significant change was seen in physical functioning or pain measures. Sensitivity analyses excluding patients who received three or fewer sessions produced a consistent pattern of results.

These findings suggest that specialist CBT for FND delivered in routine clinical practice is associated with meaningful improvements in distress, functioning, and key cognitive-behavioural maintenance processes, supporting its role within multidisciplinary care.

## Linked entities

- **Diseases:** functional neurological disorder (MONDO:0002104)

## Full-text entities

- **Diseases:** pain (MESH:D010146), functional impairment (MESH:D003072), anxiety (MESH:D001007), FND (MESH:D003291), depression (MESH:D003866)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

41 references — full list in the complete paper: https://tomesphere.com/paper/PMC13021667/full.md

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Source: https://tomesphere.com/paper/PMC13021667