# Electrochemical Three‐Component Synthesis of Vinyl Sulfonamides via Decarboxylative Sulfonylation of Cinnamic Acids

## TL;DR

A new metal-free electrochemical method efficiently produces vinyl sulfonamides using cinnamic acids, SO2, and amines under mild conditions.

## Contribution

A sustainable, scalable, and selective electrochemical method for synthesizing vinyl sulfonamides without metals.

## Key findings

- The reaction uses biobased cinnamic acid derivatives and SO2 stock solutions with graphite electrodes.
- It achieves high regio- and stereoselectivity under mild conditions.
- Electrodes and electrolytes are reusable, supporting sustainable synthesis.

## Abstract

An efficient, electrochemical three‐component reaction for the synthesis of vinyl sulfonamides from cinnamic acids, SO2, and amines is reported. This metal‐free protocol utilizes inexpensive graphite electrodes and easy‐to‐use SO2 stock solutions to facilitate a decarboxylative transformation under mild conditions. The reaction proceeds with high regio‐ and stereoselectivity. The use of cinnamic acid derivatives as biobased feedstocks, combined with the demonstrated scalability and electrode/electrolyte reusability, highlights the potential of this approach for a sustainable synthesis of the important vinyl sulfonamide scaffold.

An efficient, metal‐free electrochemical three‐component reaction of cinnamic acids, SO2, and amines to access (E)‐β‐styryl sulfonamides is reported. Utilizing graphite electrodes and SO2 stock solutions, this decarboxylative protocol proceeds under mild conditions with high regio‐ and stereoselectivity. Scalability, electrode/electrolyte reusability, and renewable feedstocks underscore its sustainable synthetic potential.© 2026 WILEY‐VCH GmbH