# Circulating DPP3 limits efficacy of angiotensin II infusion in septic shock

**Authors:** Dirk van Lier, Karine Santos, Oliver Hartmann, Matthijs Kox, Peter Pickkers

PMC · DOI: 10.1186/s13054-026-05971-5 · 2026-03-25

## Full-text entities

- **Genes:** REN (renin) [NCBI Gene 5972] {aka ADTKD4, HNFJ2, RTD}, AP2B1 (adaptor related protein complex 2 subunit beta 1) [NCBI Gene 163] {aka ADTB2, AP105B, AP2-BETA, CLAPB1}, AGT (angiotensinogen) [NCBI Gene 183] {aka ANHU, SERPINA8, hFLT1}, DPP3 (dipeptidyl peptidase 3) [NCBI Gene 10072] {aka DPPIII}
- **Diseases:** septic (MESH:D001170), vasoplegic syndrome (MESH:D056987), -II (MESH:C537730), CRVS (MESH:D012769), organ failure (MESH:D009102), sepsis (MESH:D018805)
- **Chemicals:** Norepinephrine (MESH:D009638), 4Teen4 (-), Procizumab (MESH:C000717530), Catecholamine (MESH:D002395)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC13019832/full.md

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Source: https://tomesphere.com/paper/PMC13019832