Oxidative stress markers and atherogenic lipid alterations among chronic smokers
Gaurang Hasmukhbhai Suhagiya, Soham V Shah, Krupa Rajeshbhai Gondaliya, Aditi Singh, Gazal Mangukiya, Huma Saiyad
TL;DR
Chronic smoking increases oxidative stress and alters lipid levels, raising cardiovascular risk.
Contribution
Identifies oxidative stress markers and lipid changes as cardiovascular risk predictors in smokers.
Findings
Smokers had higher MDA levels and lower SOD and CAT activities.
Dyslipidemia and higher Atherogenic Index of Plasma were linked to oxidative stress.
Oxidative stress markers may predict cardiovascular risk in smokers.
Abstract
The constant entry of exogenous reactive oxygen species makes cigarette smoking one of the key contributors to systemic oxidative stress. Therefore, it is interest to compare the oxidative stress markers and lipid profiles of chronic smokers and age matched non-smokers. A cross-sectional examination of 200 males showed that serum Malondialdehyde (MDA) level was much higher and the SOD and CAT activities were much lower among smokers. Dyslipidemia and higher Atherogenic Index of Plasma were strongly positively related to oxidative stress. Thus, those oxidative biomarkers are potential cardiovascular risk predictors in chronic smokers.
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Taxonomy
TopicsAntioxidant Activity and Oxidative Stress · Advanced Glycation End Products research · Alcohol Consumption and Health Effects