# The application of MTA in single visit apexification treatment: A prospective study

**Authors:** S.K Mahboob Rahaman, Sagolsem Chandarani, Anuradha Mukherjee, Thara Elizabeth Jes, Prantika Mandal, Abhijeet Buragohain

PMC · DOI: 10.6026/973206300214741 · 2025-12-15

## TL;DR

This study shows that using MTA in a single visit can effectively create a calcified barrier in non-vital immature teeth.

## Contribution

The novelty is demonstrating MTA's effectiveness in one-visit apexification for immature teeth.

## Key findings

- Radiographic analysis showed calcified barrier formation in most cases.
- One-visit MTA apexification is effective for immature non-vital teeth.

## Abstract

Apexification is a treatment procedure used to induce a calcified barrier at the apex of an immature tooth with an open root canal,
often as a result of pulpal necrosis or trauma. Hence, this prospective study evaluates the clinical efficacy of mineral trioxide aggregate
(MTA) in achieving apexification in a cohort of 85 patients with immature, non-vital teeth. A total of 85 patients with immature permanent
teeth requiring apexification were enrolled in this prospective clinical study. Each patient underwent a one-visit apexification procedure
using MTA as the apical barrier material. Radiographic analysis showed the formation of a calcified barrier in most cases. Thus, one-visit
apexification using MTA is an effective and efficient technique for managing immature, non-vital teeth.

## Linked entities

- **Chemicals:** MTA (PubChem CID 439176)

## Full-text entities

- **Diseases:** pulpal necrosis (MESH:D003784), trauma (MESH:D014947)
- **Chemicals:** MTA (MESH:C086631)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC13018424