# Volumetric changes associated with immediate implant placement and Bio-Oss collagen

**Authors:** Harsh Ranjan, Shamna Alathankandy Vaniyanveetti, Srilekha Pulivarthi, Sachin Gendlalji fulbe, Muzammil Moin Ahmed, Manaswini Draksharapu, Md Kafeel Ahmed

PMC · DOI: 10.6026/973206300214469 · 2025-12-15

## TL;DR

Using Bio-Oss collagen during immediate dental implant placement helps preserve bone volume better than not using it.

## Contribution

This study demonstrates that Bio-Oss collagen reduces bone resorption after immediate implant placement.

## Key findings

- Bio-Oss Collagen significantly reduced volumetric bone resorption.
- Peri-implant hard tissue dimensions were better preserved with Bio-Oss Collagen.
- CBCT scans showed measurable differences in bone volume over six months.

## Abstract

Volumetric changes associated with immediate implant placement and Bio-Oss collagen is observed. Hence, Thirty patients requiring
single-tooth extraction and immediate implant placement in the anterior maxilla were randomly allocated into two groups: Group A (n=15)
received immediate implants with Bio-Oss Collagen filling the gap and Group B (n=15) received immediate implants without grafting.
Cone-beam computed tomography (CBCT) scans were obtained immediately post-operatively and at six months. Volumetric measurements were
performed using three-dimensional image analysis software. Statistical analysis included paired and independent t-tests. Bio-Oss
Collagen significantly reduced volumetric bone resorption following immediate implant placement, demonstrating superior preservation of
peri-implant hard tissue dimensions compared to non-grafted sites.

## Full-text entities

- **Chemicals:** Bio-Oss Collagen (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC13018422