# Current perspectives on bioceramic sealers in endodontics: A review

**Authors:** Lakshmi Durga Alekhya Donipudi, Farzana Shereen, Venkata Soundarya Kolaparthi, Sana Fadlalla, Pranitha Presingu, Huma Tahir

PMC · DOI: 10.6026/973206300214599 · 2025-12-15

## TL;DR

This review explores bioceramic sealers in dentistry, highlighting their benefits and challenges in root canal treatments.

## Contribution

The paper provides an updated overview of bioceramic sealers, focusing on their clinical applications and future innovations.

## Key findings

- Bioceramic sealers improve biocompatibility and regenerative potential in endodontic treatments.
- Nanotechnology and improved material properties may enhance the performance of these sealers.
- Long-term clinical studies are needed to confirm their effectiveness in regenerative endodontics.

## Abstract

Bioceramic sealers, particularly calcium silicate-based formulations, have transformed endodontic therapy through superior biocompatibility,
sealing and regenerative potential. Their chemical and mechanical interaction with dentin enhances long-term treatment outcomes. Therefore,
it is of interest to summarize recent developments in their composition, mechanisms of action, classification, clinical applications and
retreatment challenges, noting limitations such as retrievability, handling and cost. Emerging innovations, including nanotechnology and
enhanced material rheology, may enhance clinical performance, with long-term clinical studies needed to validate their role in regenerative
endodontics.

## Full-text entities

- **Chemicals:** calcium silicate (MESH:C031293)

---
Source: https://tomesphere.com/paper/PMC13018418