# Role of digital triradius variants and hypothenar patterns in early screening of primary amenorrhea

## TL;DR

This study shows that analyzing hand ridge patterns can help identify genetic risks in women with primary amenorrhea.

## Contribution

The study introduces the 'ATD' angle as a potential non-invasive screening tool for genetic abnormalities in primary amenorrhea.

## Key findings

- Females with primary amenorrhea had significantly higher mean 'ATD' angles than controls.
- Right-left asymmetry in 'ATD' angles was greater in cases compared to controls.

## Abstract

Dermatoglyphics, the study of epidermal ridge patterns, is associated with various genetic disorders. Primary amenorrhea, a condition
with multifactorial and often genetic etiology, may show distinct dermatoglyphic traits. Hence, the 'ATD' angle was measured in 40 females
with primary amenorrhea and 60 healthy controls. Data revealed significantly higher mean 'ATD' angles and greater right-left asymmetry in
cases compared to controls. Thus, we show that dermatoglyphic analysis, particularly of the 'ATD' angle, can serve as a simple, non-invasive
screening tool for identifying individuals at risk of genetic abnormalities in primary amenorrhea.