# Effect of sleep deprivation and stress on periodontal disease: A clinico-biochemical Study

**Authors:** Pratisha Rahulkar, Laxman Boyapati, Abhigna Parikipandla, Aravind Kumar, Devarathnamma M.V, Pramod V, Miral Mehta

PMC · DOI: 10.6026/973206300214459 · 2025-12-15

## TL;DR

This study explores how stress and poor sleep affect periodontal disease through clinical and biochemical measures.

## Contribution

The study provides new insights into the relationship between lifestyle factors and periodontal disease using clinical and biochemical indicators.

## Key findings

- Periodontal disease is associated with stress and sleep deprivation.
- Clinical indices like CAL and PPD correlate with lifestyle factors.
- Serum cortisol levels showed minimal variation across groups.

## Abstract

Chronic stress and poor sleep are important lifestyle factors influencing that can influence the onset and progression of periodontal
disease. Hence, a clinical biochemical study was conducted on 30 participants aged 25-50 years at Meghna Institute of Dental Sciences.
Subjects were divided into three groups and FMBS, FMPS, PPD, CAL were recorded. Stress was measured using the 10-item Perceived Stress
Scale (IPSS-10) and sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). It is found that periodontal disease is
associated with stress, sleep deprivation and clinical indices such as CAL and PPD, while serum cortisol levels exhibited minimal variation
across groups; the interplay of lifestyle factors highlights the need for a holistic approach to periodontal care.

## Linked entities

- **Diseases:** periodontal disease (MONDO:0002635)

## Full-text entities

- **Diseases:** periodontal disease (MESH:D010510), sleep deprivation (MESH:D012892), Stress (MESH:D000079225), PPD (MESH:C535387)
- **Chemicals:** cortisol (MESH:D006854)

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Source: https://tomesphere.com/paper/PMC13018392