Linking hypertension and TyG-WC circumference index among Indian adults: A cross-sectional study

TL;DR

This study explores how the TyG-WC index can predict hypertension in Indian adults aged 18-45, showing it is a strong non-invasive predictor.

Contribution

The study introduces the TyG-WC index as a novel non-invasive predictor of hypertension in young and middle-aged Indian adults.

Findings

The TyG-WC index showed the strongest predictive power for hypertension with an AUC of 0.678.

The index is significantly correlated with hypertension in young and middle-aged Indian adults.

Abstract

Prediction of hypertension using indicators such as triglyceride-glucose - waist circumference (TyG-WC) index among Indian adults is
gaining momentum in healthcare prognosis and diagnosis for adequate treatment. Therefore, it is of interest to evaluate the TyG-WC index
as a non-invasive predictor of hypertension in Indian adults aged 18-45 years. Hence, a cross-sectional study was conducted involving 58
newly diagnosed hypertensive subjects and 72 healthy controls. Independent variables included weight, BMI, WC, TyG and TyG-WC, while
hypertension served as the dependent variable, with adjustments for lifestyle and biochemical covariates. Logistic regression and ROC
curve analyses were used to assess the association and predictive accuracy of these biomarkers for hypertension. The TyG-WC index
demonstrated the strongest predictive power for hypertension (AUC = 0.678, 95% CI: 0.662-0.696, P < 0.001), indicating a significant
correlation in young and middle-aged adults.