# Application of AI in predicting postoperative infections using routine blood parameters

**Authors:** Angshuman De, Vasantavada Venkata Satya Sai Preeti, Mukul Singh, Mukesh Kumar Patwa, Niyati Pandya, Amrit Podder, Parth Jani, Chandan Gogoi

PMC · DOI: 10.6026/973206300214271 · 2025-12-15

## TL;DR

This paper shows how AI can predict postoperative infections using blood markers like CRP and NLR, with high accuracy.

## Contribution

A novel AI approach using routine blood parameters to predict postoperative infections is introduced and validated.

## Key findings

- A Random Forest model achieved an AUC of 0.93 in predicting postoperative infections.
- CRP and NLR were identified as the most influential predictors in the model.

## Abstract

The application of artificial intelligence in predicting postoperative infections using routine blood parameters is of interest.
Hence, a cohort of 120 surgical patients was analyzed and machine learning models were developed using WBC, CRP, NLR and other markers.
The Random Forest model achieved the highest predictive performance with an AUC of 0.93. CRP and NLR were identified as the most
influential predictors. Thus, we show the integration of AI for early infection detection in surgical care.

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** infection (MESH:D007239), postoperative infections (MESH:D013530)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC13018373