# Assessment of chronic liver disease using shear wave elastography: Correlation with serum markers

## TL;DR

This study shows that shear wave elastography is a reliable non-invasive tool for assessing liver fibrosis in chronic liver disease patients.

## Contribution

The study identifies optimal SWE cutoffs and confirms strong correlations with serum markers like APRI.

## Key findings

- SWE strongly correlates with APRI (r=0.70) and platelet count (r=-0.70).
- Optimal SWE cutoffs for significant fibrosis and cirrhosis are 9.2 kPa and 15.38 kPa, respectively.
- Combining SWE with APRI provides a reliable non-invasive fibrosis assessment.

## Abstract

Chronic liver disease requires accurate fibrosis assessment, with non-invasive tools gaining importance over biopsy. Hence, this cross-
sectional study evaluated liver fibrosis in 122 CLD patients using shear wave elastography (SWE) and correlated findings with serum markers.
SWE showed strong correlation with APRI (r=0.70) and platelet count (r=-0.70), and moderate correlations with AST and FIB-4. Optimal SWE
cutoffs were 9.2 kPa for significant fibrosis and 15.38 kPa for cirrhosis, with excellent diagnostic accuracy (AUROC=0.99). SWE combined
with serum markers-especially APRI-provides a reliable, non-invasive alternative for fibrosis assessment in CLD patients.