# Effect of I-PRF and alloplastic bone material in periodontal osseous defects - A case series

## TL;DR

This study shows that combining i-PRF with a bone graft material improves periodontal healing in patients with chronic periodontitis.

## Contribution

The study demonstrates enhanced periodontal regeneration using i-PRF with alloplastic bone grafts in a clinical setting.

## Key findings

- Patients showed reduced probing pocket depth after 6 months.
- Clinical attachment level improved significantly following treatment.
- Radiographic evidence indicated increased bone fill in treated areas.

## Abstract

Periodontal regeneration in patients with chronic periodontitis remains a clinical challenge due to limited predictability of current
regenerative materials and techniques. This case series was conducted on 10 patients diagnosed with moderate to advanced chronic periodontitis.
Participants received i-PRF with Hydroxyapatite bone graft. Clinical parameters and radiographic bone defect depth were measured at baseline
and after 6 months. Following surgical intervention, patients exhibited greater reductions in PPD, gains in CAL and increased bone fill
suggesting that i-PRF may enhance periodontal regeneration when used in conjunction with alloplastic bone grafts.