Residual monomer release from different acrylic-based dental materials: An in vivo evaluation

TL;DR

This study evaluates how much harmful monomer is released from different dental materials in children and finds thermoformed sheets to be the safest option.

Contribution

The study provides in vivo evidence on monomer release from various acrylic dental materials in pediatric patients.

Findings

Auto polymerising acrylics released significantly more monomer than heat-cured materials.

Thermoformed sheets showed no detectable monomer release.

Monomer levels were measured in saliva at multiple time points after appliance insertion.

Abstract

Primary concern from residual monomer and other leachable components from denture base resins is allergic and sensitivity reactions
among patients. Therefore, it is of interest to evaluate the leaching ability of residual methylmethacrylate monomer from heat polymerising
acrylic, auto polymerising acrylic, auto polymerising acrylic cured under pot pressure, and thermoformed sheets in 40 children aged 7-14
years. Saliva samples were collected at 5 minutes, 1 hour, 24 hours, and 1 month after appliance insertion and analyzed by High Performance
Liquid Chromatography. Results revealed significantly higher monomer release from auto polymerising acrylic materials, followed by heat
cure, while thermoformed sheets showed no detectable release. The findings indicate thermoformed sheets are safer and more clinically
acceptable alternatives for pediatric appliances.