# Management of type 2 diabetes mellitus using Yoga: Implications for immunological and autonomic dysfunction

**Authors:** Rukadikar C.A, Geetha M, Dixit A.M, Renuka K, Vinoth R, Nishad S, Rukadikar A.R, Singh M.K

PMC · DOI: 10.6026/973206300214777 · 2025-12-15

## TL;DR

This paper explores how yoga can help manage type 2 diabetes by improving immune function and autonomic nervous system health.

## Contribution

The study highlights yoga as a novel complementary therapy for neuro-immunological and autonomic dysfunction in T2DM.

## Key findings

- Yoga improves glycaemic control and autonomic balance in individuals with T2DM.
- Yoga may mitigate neuro-immunological dysregulation and enhance cardiovascular health.
- Yoga supports neuro-endocrine functioning in those with T2DM.

## Abstract

Type 2 diabetes mellitus (T2DM) is characterized by chronic hyperglycaemia, insulin resistance and β-cell dysfunction, leading to
systemic inflammation and autonomic nervous system impairment. Diabetic autonomic neuropathy and cardiac autonomic neuropathy significantly
increase risks of cardiovascular morbidity and mortality. Metabolic disturbances such as oxidative stress, polyol pathway activation and
AGEs contribute to progressive neuronal and microvascular injury. Emerging evidence shows that yoga improves glycaemic control, autonomic
balance and neuro-endocrine functioning in individuals with T2DM. Thus, we show that yoga as a complementary therapeutic approach to
mitigate neuro-immunological dysregulation and enhance cardiovascular health in T2DM.

## Linked entities

- **Diseases:** type 2 diabetes mellitus (MONDO:0005148), diabetic autonomic neuropathy (MONDO:0001299)

## Full-text entities

- **Diseases:** beta-cell dysfunction (MESH:D007340), dysregulation (MESH:D021081), insulin resistance (MESH:D007333), cardiac autonomic neuropathy (MESH:D006331), T2DM (MESH:D003924), Diabetic autonomic neuropathy (MESH:D003929), neuronal and microvascular injury (MESH:D017566), autonomic nervous system impairment (MESH:D001342), inflammation (MESH:D007249)
- **Chemicals:** polyol (MESH:C024617)

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Source: https://tomesphere.com/paper/PMC13018327