# Periodontal regeneration with Bio-Oss for intrabony defect management: A case report

**Authors:** K. Lakshmi Priya, Uma Subbiah, Sarumathi D, Sruthika G, Pavithra D, Jaideep Mahendra

PMC · DOI: 10.6026/973206300214659 · 2025-12-15

## TL;DR

This case report shows successful periodontal regeneration using Bio-Oss and a GTR membrane in a patient with localized chronic periodontitis.

## Contribution

Demonstrates the effectiveness of xenograft-based regenerative therapy for intrabony defects in localized chronic periodontitis.

## Key findings

- Clinical follow-up showed a marked reduction in pocket depth.
- Radiographic imaging revealed significant bone fill in the treated area.

## Abstract

The goal of periodontal therapy is to preserve and regenerate the supporting structures of teeth affected by periodontitis. This report
presents the management of an intrabony defect associated with teeth 16 and 17 in a 37-year-old female patient using demineralized bovine
bone mineral (Bio-Oss®; Geistlich Pharma AG, Switzerland) and a GTR membrane (Bio-Gide®; Geistlich Pharma AG, Switzerland). Following
initial non-surgical therapy, open flap debridement with regenerative treatment was performed. Clinical and radiographic follow-ups at
one, three, and six months demonstrated a marked reduction in pocket depth and radiographic bone fill, indicating successful periodontal
regeneration. Thus, we show the effectiveness of xenograft-based regenerative therapy in localized chronic periodontitis.

## Linked entities

- **Diseases:** periodontitis (MONDO:0005076)

## Full-text entities

- **Diseases:** periodontitis (MESH:D010518), intrabony defect (MESH:D000013), chronic periodontitis (MESH:D055113)
- **Chemicals:** GTR (-), Bio-Oss (MESH:C077540)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC13018325