# Video-assisted thoracoscopic blebotomy for spontaneous pneumothorax treatment using the no-knife endoscopic stapler

**Authors:** Sunghoon Kim, Gabriella Grisotti, Olajire Idowu

PMC · DOI: 10.1007/s00383-026-06391-w · 2026-03-25

## TL;DR

This study shows that using a no-knife stapler for blebotomy in treating pneumothorax is safe, effective, and reduces postoperative pain compared to traditional methods.

## Contribution

The study introduces a novel thoracoscopic technique using a no-knife stapler without pleurodesis for treating spontaneous pneumothorax.

## Key findings

- Eight patients underwent the procedure with no intraoperative or postoperative complications.
- Median chest tube duration was 2 days and mean postoperative pain score was 1.3.
- No pneumothorax recurrence was observed during a median follow-up of 24 months.

## Abstract

A standard treatment for pneumothorax due to bleb rupture is thoracoscopic blebectomy, often combined with pleurodesis to reduce recurrence risk. However, pleurodesis can cause significant postoperative pain. This study evaluates the efficacy of the no-knife endoscopic stapler blebotomy without pleurodesis using video-assisted thoracoscopic surgery (VATS) for spontaneous pneumothorax.

We conducted a retrospective chart review of patients treated with no-knife endoscopic stapler blebotomy for spontaneous pneumothorax at UCSF Benioff Children’s Hospital Oakland from 2020 to 2024. The procedure involved using the no-knife endoscopic stapler for blebotomy without performing pleurodesis. Post-procedure air leaks were monitored with a chest tube. We analyzed postoperative chest tube duration, pain levels, and recurrence rates.

The study included eight male patients with a median age of 17 (range 15-19). Apical blebs were identified thoracoscopically in all patients and stapled off using the no-knife stapler. No intraoperative or postoperative complications occurred. The median postoperative chest tube duration was 2 days (range 1-3). The mean pain score on postoperative day 1 was 1.3 (range 0-10). Over a median follow-up of 24 months (range 6-36), no pneumothorax recurrence was observed.

No-knife endoscopic stapler thoracoscopic blebotomy is a safe and effective procedure. Avoiding pleurodesis reduces postoperative pain and morbidity.

Level 4, Observational study.

## Linked entities

- **Diseases:** pneumothorax (MONDO:0002076)

## Full-text entities

- **Diseases:** incisional pain (MESH:D000069290), cystic fibrosis (MESH:D003550), infection (MESH:D007239), chest pain (MESH:D002637), bleb rupture (MESH:D012421), interstitial lung disease (MESH:D017563), lung collapse (MESH:D001261), inflammation (MESH:D007249), chronic obstructive pulmonary disease (MESH:D029424), dyspnea (MESH:D004417), lung disease (MESH:D008171), acute respiratory distress syndrome (MESH:D012128), necrosis (MESH:D009336), emphysema (MESH:D004646), postoperative pain (MESH:D010149), Pain (MESH:D010146), air (MESH:D004618), fever (MESH:D005334), SP (MESH:D011030)
- **Chemicals:** talc (MESH:D013627), oxycodone (MESH:D010098), oxygen (MESH:D010100), Pleurovac (-), morphine (MESH:D009020), doxycycline (MESH:D004318), Ropivacaine (MESH:D000077212), acetaminophen (MESH:D000082), ibuprofen (MESH:D007052), Carbon dioxide (MESH:D002245), ketorolac (MESH:D020910)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13018058/full.md

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Source: https://tomesphere.com/paper/PMC13018058