# Impaired awareness of hypoglycemia: can structured education address this persistent challenge?

**Authors:** Yuanyuan Chen, Xiaowen He, Yanmin Shan, Meijuan Lan

PMC · DOI: 10.3389/fendo.2026.1722045 · Frontiers in Endocrinology · 2026-03-12

## TL;DR

This paper explores how structured education and new technologies might help diabetic patients who struggle to recognize low blood sugar.

## Contribution

The paper proposes integrating cognitive interventions into structured education as a novel approach to managing impaired hypoglycemia awareness.

## Key findings

- Impaired Awareness of Hypoglycemia is linked to severe hypoglycemia and emotional disturbances.
- Structured education is key but often insufficiently implemented.
- Combining education with cognitive interventions may offer new solutions.

## Abstract

Impaired Awareness of Hypoglycemia (IAH) describes a condition in insulin-treated diabetic patients characterized by a diminished ability to perceive the onset of acute hypoglycemia. With an estimated prevalence ranging from 23.2% to 26.3%, IAH is associated with a significantly elevated risk of severe hypoglycemia (SH) and is increasingly linked to emotional disturbances. As a major challenge in diabetes management, the primary interventions for IAH include structured education and diabetes technology. However, the real-world impact of diabetes technology on the frequency of SH and IAH remains contentious. While structured education is fundamental for addressing IAH, its implementation is often inadequate, and program content requires optimization, thereby limiting the effectiveness of current educational approaches. Consequently, there is a persistent need for enhanced treatment strategies. With advancements in intelligent technology, a hybrid model integrating structured education with diabetes technology is emerging as a promising trend. Furthermore, IAH can contribute to cognitive dysfunction, which in turn impairs the ability to perceive and respond to hypoglycemic events. This suggests that incorporating cognitive interventions into structured education may represent a novel therapeutic avenue and potentially yield innovative management solutions.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015), hypoglycemia (MONDO:0004946)

## Full-text entities

- **Diseases:** diabetes (MESH:D003920), emotional disturbances (MESH:D014832), cognitive dysfunction (MESH:D003072), IAH (MESH:D007003), SH (MESH:D045169)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC13017378/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC13017378/full.md

## References

77 references — full list in the complete paper: https://tomesphere.com/paper/PMC13017378/full.md

---
Source: https://tomesphere.com/paper/PMC13017378