# Duodenal and cutaneous metastases from advanced rectal cancer: a rare case report

## TL;DR

A rare case of rectal cancer spreading to the duodenum and skin showed significant improvement with fruquintinib treatment.

## Contribution

Demonstrates fruquintinib's potential efficacy in rare rectal cancer metastases.

## Key findings

- Patient showed rapid regression of cutaneous lesions with fruquintinib.
- Fruquintinib may be effective for aggressive, rare rectal cancer metastases.
- Case highlights the need for targeted therapies in uncommon cancer presentations.

## Abstract

Duodenal and cutaneous metastases from rectal cancer are rare and associated with poor prognosis. This case report describes a patient with advanced rectal cancer who developed these uncommon metastases after first-line therapy. Upon treatment with fruquintinib, the patient experienced a rapid and significant regression of the cutaneous lesions, demonstrating a visible clinical response. This suggests that fruquintinib may be an effective therapeutic option for patients with such aggressive and rare metastatic disease.