# Amebic liver abscess with bronchopleural fistula

**Authors:** Michaela Schumacher, Andrea Erba, Seraina Bally, Seraina Frei, Maja Weisser Rohacek, Andreas Neumayr, Anne-Valérie Burgener-Gasser

PMC · DOI: 10.1093/jtm/taag006 · Journal of Travel Medicine · 2026-01-28

## TL;DR

Amebic liver abscess with a bronchopleural fistula in a traveler was diagnosed quickly using PCR, avoiding unnecessary antibiotics.

## Contribution

Rapid diagnosis of amebic liver abscess using PCR on abscess fluid is highlighted as a novel approach for targeted treatment.

## Key findings

- PCR on abscess fluid enabled rapid diagnosis of amebic liver abscess.
- Targeted therapy was initiated within 24 hours, avoiding broad-spectrum antibiotics.

## Abstract

Amebic liver abscess with bronchopleural fistula caused by Entamoeba histolytica can mimic severe bacterial sepsis in a returning traveller. Rapid diagnosis via multiplex Polymerase Chain Reaction (PCR) on abscess fluid enabled targeted therapy within 24 h, avoiding unnecessary broad-spectrum antibiotics. Intestinal amebiasis should be considered in patients with compatible symptoms and relevant exposure.

## Linked entities

- **Diseases:** intestinal amebiasis (MONDO:0024275)
- **Species:** Entamoeba histolytica (taxon 5759)

## Full-text entities

- **Diseases:** Amebic liver abscess (MESH:D008101), fistula (MESH:D005402), bacterial sepsis (MESH:D001424), Intestinal amebiasis (MESH:D004404), abscess (MESH:D000038)
- **Species:** Entamoeba histolytica (species) [taxon 5759], Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC13017085/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13017085/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC13017085/full.md

---
Source: https://tomesphere.com/paper/PMC13017085