# Ultrasound-derived tibia-fascia angle for noninvasive assessment of intracompartmental pressure in tibial plateau fractures

**Authors:** Heng Zhang, Luqi Li, Huiyang Jia, Haofei Wang, Qi Dong, Jialiang Guo, Heping Deng, Zhiyong Hou

PMC · DOI: 10.1371/journal.pone.0344990 · PLOS One · 2026-03-25

## TL;DR

This study explores using ultrasound to measure the tibia-fascia angle as a noninvasive way to estimate pressure in leg fractures, offering a faster alternative to current methods.

## Contribution

The study introduces the tibia-fascia angle as a novel noninvasive surrogate for intracompartmental pressure in tibial plateau fractures.

## Key findings

- ΔTFA showed significant linear correlation with intracompartmental pressure (β = 1.74 mmHg/°).
- ΔTFA achieved 86.5% sensitivity and 52.9% specificity for detecting high compartment pressure.
- The method demonstrates moderate diagnostic accuracy as a screening tool for high compartment pressure.

## Abstract

Current noninvasive diagnostics for acute compartment syndrome (ACS) lack clinical practicality and reliability. This study aimed to evaluate ultrasound-derived tibia-fascia angle (TFA) as a novel morphometric surrogate for intracompartmental pressure (ICP) assessment.

In this observational study, 105 patients with closed tibial plateau fractures were enrolled at a tertiary trauma center. TFA was bilaterally measured using B-mode ultrasound by blinded operators. Invasive ICP served as the reference standard. Correlations were analyzed via Spearman correlation analysis and multivariable linear regression, and diagnostic performance for high compartment pressure (HCP, ICP > 30 mmHg) was assessed using ROC analysis.

ΔTFA showed a significant linear correlation with ICP after adjustment for confounders (β = 1.74 mmHg/°, 95% CI: 1.07–2.41, Padj < 0.001) and a moderate monotonic association (ρ = 0.545, 95%CI: 0.395–0.667, P < 0.001). For detecting HCP, ΔTFA achieved an area under the receiver operating characteristic curve (AUC) of 0.716 (95% CI: 0.621–0.812), with 86.5% sensitivity and 52.9% specificity at the optimal cutoff (ΔTFA ≥ 4.9°).

ΔTFA provides a rapid, operator-friendly method for noninvasive ICP estimation, demonstrating moderate diagnostic accuracy as a screening tool for HCP in tibial plateau fractures. Its integration into trauma workflows could enhance early risk stratification, particularly for high-energy fractures, though specificity limitations warrant complementary confirmatory tests.

## Full-text entities

- **Diseases:** blunt trauma (MESH:D014949), paresthesia (MESH:D010292), Injury (MESH:D014947), infection (MESH:D007239), Pallor (MESH:D010167), falls (MESH:C537863), arterial injury (MESH:D057772), I-III fractures (MESH:C564683), pain (MESH:D010146), ACS (MESH:D000208), muscle and nerve damage (MESH:D009133), Ischemia (MESH:D007511), lower extremity injuries (MESH:D010291), neuromuscular pathologies (MESH:D009468), muscle necrosis (MESH:D009135), polytrauma (MESH:D009104), HCP (MESH:D046349), tibial plateau fracture (MESH:D000092463), paralysis (MESH:D010243), burns (MESH:D002056), HCP (MESH:D006973), II (MESH:C537730), Schatzker type IV-VI fractures (MESH:C000631847), pulselessness (MESH:D013625), crush injuries (MESH:D000071576), edema (MESH:D004487), Schatzker IV-VI fractures (MESH:D006011), Fracture (MESH:D050723)
- **Chemicals:** DeltaTFA (-)
- **Species:** Homo sapiens (human, species) [taxon 9606], Oryctolagus cuniculus (domestic rabbit, species) [taxon 9986]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC13016300/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13016300/full.md

## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC13016300/full.md

---
Source: https://tomesphere.com/paper/PMC13016300