# Gastric MALT Lymphoma in Plummer-Vinson Syndrome: Broadening the Spectrum of Associated Malignancies

## TL;DR

A 59-year-old man with Plummer-Vinson syndrome was found to have gastric MALT lymphoma, a previously unreported cancer association.

## Contribution

This is the first reported case linking gastric MALT lymphoma with Plummer-Vinson syndrome.

## Key findings

- Gastric MALT lymphoma was identified in a patient with Plummer-Vinson syndrome.
- This case expands the known malignancy spectrum associated with PVS.
- Thorough evaluation is recommended for malignancies in PVS patients with iron deficiency anemia.

## Abstract

Plummer-Vinson syndrome (PVS) is a constellation of symptoms associated with iron deficiency anemia, esophageal web formation, and squamous cell cancer, typically of the esophagus and pharynx. PVS has rarely been associated with gastric cancer. We report a case of a 59-year-old man found to have PVS with gastric mucosa-associated lymphoid tissue lymphoma, an association to our knowledge not previously described in the literature. This case expands the spectrum of malignancies that may be encountered in patients with PVS and highlights the importance of thorough evaluation for malignancy in patients presenting with iron deficiency anemia.