# Oestrus ovis Nasal Myiasis with Pupation in Human Host, Greece, October 2025

**Authors:** Ilias P. Kioulos, Emmanouil Kokkas, Evangelia-Theophano Piperaki

PMC · DOI: 10.3201/eid3203.251077 · 2026-03-01

## TL;DR

A rare case of nasal myiasis caused by Oestrus ovis was reported in Greece, where the larvae developed into pupae inside a human host.

## Contribution

This is the first documented case of Oestrus ovis nasal myiasis in a human with pupation occurring within the host.

## Key findings

- Ten larvae and one puparium were found in the patient’s maxillary sinus.
- Diagnosis was confirmed using morphological analysis and DNA sequencing.

## Abstract

We report a case of human Oestrus ovis nasal myiasis in Greece, in which pupation occurred within the human host. Ten larvae in various stages of development and 1 puparium were expelled or extracted from the patient’s maxillary sinus. Diagnosis was confirmed through morphologic identification and by PCR, followed by DNA sequencing.

## Linked entities

- **Species:** Oestrus ovis (taxon 123737), Homo sapiens (taxon 9606)

## Full-text entities

- **Genes:** COX1 (cytochrome c oxidase subunit I) [NCBI Gene 4512] {aka COI, MTCO1}
- **Diseases:** maxillary pain (MESH:D010146), O. ovis (MESH:C535508), conjunctivitis (MESH:D003231), coughing (MESH:D003371), septum deviation (MESH:D000093665), Myiasis (MESH:D009198)
- **Species:** Ovis aries (domestic sheep, species) [taxon 9940], Homo sapiens (human, species) [taxon 9606], Oestrus ovis (sheep bot fly, species) [taxon 123737], Capra hircus (domestic goat, species) [taxon 9925]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC13016021/full.md

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Source: https://tomesphere.com/paper/PMC13016021