# Extraintestinal Entamoeba moshkovskii Infection, Eastern India

**Authors:** Sanjib Kumar Sardar, Ajanta Ghosal, Tapas Haldar, Basudev Ganguly, Koushik Das, Sandipan Ganguly

PMC · DOI: 10.3201/eid3203.251065 · 2026-03-01

## TL;DR

A rare case of severe infection caused by Entamoeba moshkovskii, a parasite previously thought harmless, is reported in a patient from eastern India.

## Contribution

Demonstrates the pathogenic potential of E. moshkovskii through a confirmed case of extraintestinal disease.

## Key findings

- E. moshkovskii was identified as the cause of a splenic abscess and systemic symptoms in a patient.
- The case challenges the traditional view of E. moshkovskii as nonpathogenic.
- Molecular analysis confirmed the parasite's role in the severe illness.

## Abstract

Entamoeba moshkovskii is historically considered nonpathogenic. We report a case of severe extraintestinal infection in a patient from eastern India who had abdominal pain, fever, weight loss, anemia, and a splenic abscess. Molecular analysis confirmed E. moshkovskii as the causative agent. This case highlights this parasite’s potential to cause severe illness.

## Linked entities

- **Diseases:** splenic abscess (MONDO:0002333)
- **Species:** Entamoeba moshkovskii (taxon 41668)

## Full-text entities

- **Diseases:** diarrhea (MESH:D003967), fever (MESH:D005334), cough (MESH:D003371), diarrheal (MESH:D004403), hepatomegaly (MESH:D006529), necrosis (MESH:D009336), colitis (MESH:D003092), lymphadenopathy (MESH:D008206), pleural effusion (MESH:D010996), granuloma (MESH:D006099), clubbing (MESH:D003025), hepatic abscess (MESH:D008100), vomiting (MESH:D014839), hemoptysis (MESH:D006469), E. histolytica infection (MESH:D004749), intestinal amebiasis (MESH:D004404), tenderness (MESH:D063806), cyanosis (MESH:D003490), weight loss (MESH:D015431), Iron deficiency anemia (MESH:D018798), anemia (MESH:D000740), shortness of breath (MESH:D004417), nausea (MESH:D009325), extraintestinal infection (MESH:D007239), abdominal pain (MESH:D015746), amoebiasis (MESH:D000562), E. moshkovskii infection (MESH:D004927), splenomegaly (MESH:D013163), cysts (MESH:D003560), bad taste (MESH:D013651), splenic abscess (MESH:D000038)
- **Chemicals:** Metronidazole (MESH:D008795), ferrous sulfate (MESH:C020748), emetine (MESH:D004640), alcohol (MESH:D000438), meropenem (MESH:D000077731), Pigtail (-), oxygen (MESH:D010100)
- **Species:** hepatitis C virus [taxon 11103], Entamoeba dispar (species) [taxon 46681], Entamoeba bangladeshi (species) [taxon 1226471], Brucella (genus) [taxon 234], Entamoeba moshkovskii (species) [taxon 41668], Entamoeba nuttalli (species) [taxon 412467], Entamoeba (genus) [taxon 5758], Homo sapiens (human, species) [taxon 9606], Entamoeba histolytica (species) [taxon 5759], Mycobacterium tuberculosis (species) [taxon 1773], Mus musculus (house mouse, species) [taxon 10090], Human immunodeficiency virus 1 (no rank) [taxon 11676]
- **Mutations:** glutamic acid with lysine, *2 T/G, 127 G/A

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13016018/full.md

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Source: https://tomesphere.com/paper/PMC13016018