# CCHFV Seroprevalence among Hunter-Gatherers, Northeastern Democratic Republic of the Congo

**Authors:** Dacquin M. Kasumba, Samuel M. Shamamba, Ange Y. Mubiala, Bobo N. Bazola, Amanda C. Horton, Charles Ndawula, Jean-Jacques Muyembe-Tamfum, Jean-Christophe Sabue Mulangu

PMC · DOI: 10.3201/eid3203.251171 · 2026-03-01

## TL;DR

This study found a 4% CCHFV antibody presence in hunter-gatherer communities in northeastern DRC, suggesting undetected virus circulation.

## Contribution

The study reports CCHFV seroprevalence in previously unstudied hunter-gatherer populations in the DRC.

## Key findings

- 4% of 300 participants tested positive for CCHFV antibodies.
- CCHFV is likely circulating undetected in the region.
- The findings highlight the need for improved surveillance systems.

## Abstract

We evaluated human Crimean-Congo hemorrhagic fever virus (CCHFV) seroprevalence in hunter-gatherer populations of northeastern Democratic Republic of the Congo. We tested blood from 300 participants for CCHFV antibodies; 4% were CCHFV-positive. CCHFV likely has been circulating undetected in the country, indicating the need for a more robust surveillance system.

## Linked entities

- **Diseases:** Crimean-Congo hemorrhagic fever (MONDO:0020501)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** headache (MESH:D006261), HF (MESH:D006480), nausea (MESH:D009325), Infections (MESH:D007239), vomiting (MESH:D014839), fever (MESH:D005334), diarrhea (MESH:D003967), CCHF (MESH:D006479), myalgia (MESH:D063806)
- **Species:** Homo sapiens (human, species) [taxon 9606], CCHFV [taxon 1980519], Chiroptera (bats, order) [taxon 9397], Rattus norvegicus (brown rat, species) [taxon 10116]

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Source: https://tomesphere.com/paper/PMC13016016