# Detecting Influenza A(H5N1) Viruses through Severe Acute Respiratory Infection Surveillance, Cambodia

**Authors:** William W. Davis, Kathrine R. Tan, Borann Sar, Alyssa Finlay, Heng Seng, Vicheth Long, Savuth Chin, Darapheak Chau, Kim Sreng Leang, Mich Vann, Sovandara Lam, Dara Chan, Ly Vannara Tek, Sovann Ly, Timothy M. Uyeki

PMC · DOI: 10.3201/eid3203.250832 · 2026-03-01

## TL;DR

A study in Cambodia found that monitoring severe respiratory infections helped detect most H5N1 bird flu cases.

## Contribution

The study shows that SARI surveillance is effective in identifying H5N1 cases in Cambodia.

## Key findings

- 12 out of 19 H5N1 cases in Cambodia were detected through SARI surveillance or contact testing.
- SARI surveillance can complement other methods for H5N1 detection.

## Abstract

Of 19 human cases of avian influenza A(H5N1) virus infection detected during January 2023–March 2025 in Cambodia, 12 (63%) were detected directly by surveillance for severe acute respiratory infection (SARI) or indirectly by testing ill close contacts. SARI surveillance can supplement other surveillance sources for identifying H5N1 cases.

## Full-text entities

- **Diseases:** SARI (MESH:D045169)
- **Species:** H5N1 subtype (serotype) [taxon 102793], Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC13016001