# Trends in Coronavirus Disease 2019 Mortality Within a US Academic Health System, 2020–2025

**Authors:** Nicholas A Turner, Jason E Stout, Jeffrey D Jenks

PMC · DOI: 10.1093/ofid/ofag138 · 2026-03-14

## TL;DR

The study examines how mortality rates from COVID-19 have changed over time within a US academic health system from 2020 to 2025.

## Contribution

The study provides new insights into the evolving mortality trends of COVID-19 compared to influenza within a specific health system.

## Key findings

- 30-day mortality rates after a positive COVID-19 test have decreased over time.
- Adjusted mortality rates remain higher than those for influenza.
- Mortality trends were analyzed within a single academic health system from 2020 to 2025.

## Abstract

Coronavirus disease 2019 (COVID-19) was initially associated with higher mortality than other respiratory viruses. We assessed trends in mortality following a positive COVID-19 test within a single academic health system. Among individuals with COVID-19, 30-day crude and adjusted mortality rates have decreased but remain numerically similar to higher than influenza.

## Linked entities

- **Diseases:** Coronavirus disease 2019 (MONDO:0100096), influenza (MONDO:0005812)

## Full-text entities

- **Diseases:** influenza (MESH:D007251), COVID-19 (MESH:D000086382)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC13014464/full.md

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Source: https://tomesphere.com/paper/PMC13014464