# Unexpected rupture of the left ventricular wall following surgical repair of post-infarction ventricular septal rupture in a patient supported by Impella CP: a case report

**Authors:** Risa Nishio, Yusuke Takei, Yuya Nozawa, Toshiyuki Kuwata, Ikuko Shibasaki

PMC · DOI: 10.1093/ehjcr/ytag054 · 2026-01-25

## TL;DR

A patient with a heart injury required a heart pump before surgery, but the device caused a rare complication that led to a heart wall rupture during the procedure.

## Contribution

This case highlights a rare but serious complication of prolonged Impella CP use in post-infarction ventricular septal rupture management.

## Key findings

- Prolonged Impella CP support can cause left ventricular wall rupture due to mechanical contact.
- Careful monitoring and positioning of the device are essential to prevent such complications.
- The patient recovered after surgical repair despite the complication.

## Abstract

Percutaneous ventricular assist devices (pVADs) are important systems in the management of cardiogenic shock, providing effective left ventricular (LV) unloading and enabling preoperative stabilization in critically ill patients. Specifically, their use has expanded to postinfarction ventricular septal rupture (VSR), allowing for delayed surgical intervention once myocardial fibrosis progresses. Nonetheless, mechanical complications associated with prolonged pVAD support, including LV perforation, are rare but potentially fatal.

A 70-year-old woman developed VSR following an anterior myocardial infarction involving the left anterior descending artery. Preoperatively, the patient was supported with an Impella CP for 7 days. Although the device functioned normally, frequent premature ventricular contractions were noted during support. The patient underwent surgical VSR repair via the right ventricular approach using the extended sandwich patch technique. The Impella CP was removed before aortic cross-clamping. After patch closure and successful weaning from the cardiopulmonary bypass, sudden bleeding was observed in the posterior LV free wall. Re-arrest occurred, and surgical inspection revealed a 1.5-cm subepicardial rupture in the posterior wall, suspected to have resulted from mechanical contact with the Impella catheter tip. The rupture site was repaired using felt-reinforced sutures and surgical sealant. The patient later required temporary mechanical support due to low-output syndrome, but recovered gradually with preserved LV function and no VSR recurrence.

Even with a pigtail-tipped pVAD, inadequate positioning and prolonged support can lead to LV wall injuries. Careful monitoring, positional assessment, and surgical awareness are essential to avoid such complications.

## Linked entities

- **Diseases:** cardiogenic shock (MONDO:0800175)

## Full-text entities

- **Diseases:** LV perforation (MESH:D018487), rupture (MESH:D012421), anterior myocardial infarction (MESH:D056988), premature ventricular contractions (MESH:D018879), myocardial fibrosis (MESH:D005355), cardiogenic shock (MESH:D012770), low-output syndrome (MESH:D002303), bleeding (MESH:D006470), VSR (MESH:D018658), infarction (MESH:D007238)
- **Chemicals:** CP (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13014365/full.md

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Source: https://tomesphere.com/paper/PMC13014365