High efficiency of antibacterial activity-based Zn-Co@BTC MOF against Bacillus bacterial cells
Eman Abdelnasser, Ahmed A. El-Naggar, Lofty A. Lotfy, Abdulrhman M. Alaraj, Ahmed M. Eid, Antar El-Banna, Swellam W. Sharshir, Walid Ismail, Mahmoud Abdelfatah, Abdelhamid El-Shaer
TL;DR
A new metal-organic framework called Zn-Co@BTC was created and shown to strongly inhibit the growth of Bacillus bacteria, making it a promising antibacterial material for biomedical use.
Contribution
The novel Zn-Co@BTC MOF demonstrates high antibacterial efficiency against Bacillus cereus with complete growth inhibition at 800 mg/L.
Findings
Zn-Co@BTC MOF achieved 99.9% bacterial growth inhibition at 600 mg/L.
Complete inhibition (100%) was observed at 800 mg/L against Bacillus cereus.
The material showed high thermal stability and a large surface area.
Abstract
In this work, Zn-Co@BTC was synthesized under environmentally friendly, economical, and green conditions. It was prepared by the solvothermal method using zinc nitrate hexahydrate and cobalt nitrate hexahydrate as the metals, with benzene-1,3,5-tricarboxylate (BTC) as the ligand. The formation of Zn-Co@BTC MOF was confirmed by Ultraviolet–Visible spectroscopy (UV–Vis), X-ray diffraction, Fourier transform infrared, thermogravimetric analysis, Raman spectroscopy, X-ray Photoelectron Spectroscopy, Brunauer–Emmett–Teller surface area analysis, scanning electron microscopy, and Transmission electron microscopy. It exhibited high thermal stability, a large surface area, and strong antibacterial activity. The antibacterial activity was evaluated against the Bacillus cereus strain identified by 16S rRNA gene sequencing using optical density measurements and the cut plug method. The results…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 10
Figure 11
Figure 12
Figure 13
Figure 14
Figure 15
Figure 16
Figure 17
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
Figure 9Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsMetal-Organic Frameworks: Synthesis and Applications · Nanoplatforms for cancer theranostics · Magnesium Oxide Properties and Applications