# Development of herbicide-resistant peanut via prime editing and optimization of editing efficiency

## TL;DR

Scientists made peanut plants resistant to herbicides using a gene-editing technique called prime editing, but they need to improve the efficiency of the process.

## Contribution

The study introduces prime editing to confer herbicide resistance in peanut by targeting the acetolactate synthase gene.

## Key findings

- Prime editing successfully introduced the W574L mutation in acetolactate synthase, conferring herbicide resistance in peanut.
- The editing efficiency is currently suboptimal and requires further optimization for practical application.

## Abstract

Prime editing of acetolactate synthase to introduce the W574L mutation confers broad-spectrum herbicide resistance in peanut, though efficiency remains suboptimal and requires further refinement.