# Malignant Melanoma as a Rare Cause of Penile Cancer: A Case Report

## TL;DR

A 47-year-old man was diagnosed with rare penile cancer caused by malignant melanoma, highlighting its clinical presentation and treatment challenges.

## Contribution

This case report adds to the limited literature on penile malignant melanoma by detailing its clinical course and management.

## Key findings

- The patient presented with a lesion on the glans penis, progressing to severe pain and lymphadenopathy.
- Histopathology confirmed malignant melanoma, with imaging revealing lymph node and visceral metastasis.
- The case emphasizes the importance of multidisciplinary evaluation for diagnosis and treatment planning.

## Abstract

Malignant melanoma is a neoplasm originating from melanocytes and may arise at cutaneous or extracutaneous sites. Penile involvement is uncommon and may present with variable clinical manifestations. We describe a case of a 47-year-old male who presented with a progressively enlarging lesion involving the glans penis, initially associated with pruritus and later with severe local pain and bilateral inguinal lymphadenopathy. Histopathological examination of an incisional biopsy confirmed malignant melanoma of the penis. Imaging studies performed for staging demonstrated regional lymph node involvement and disseminated visceral disease. The patient underwent surgical management followed by systemic treatment after multidisciplinary evaluation. This case illustrates the clinical presentation, diagnostic approach, and management of penile malignant melanoma.