# A Quasi-experimental Study on the Use of Retrospective Case Construction to Teach Hepatobiliary Function Test Interpretation to First-Year Medical Students

**Authors:** Palani Selvam Mohanraj, Jancy K Jose, Niranjan Gopal, Amle Dnyanesh Balkrishna, Roshan Takhelmayum, Utsav Haldar, Jyoti E John, Anand Dixit

PMC · DOI: 10.7759/cureus.104082 · Cureus · 2026-02-22

## TL;DR

This study shows that using retrospective case construction helps first-year medical students better understand and retain hepatobiliary function test interpretation skills.

## Contribution

The study introduces retrospective case construction as an effective teaching method for early clinical skills in medical education.

## Key findings

- Students showed significant improvement in interpreting hepatobiliary tests, especially in identifying obstructive jaundice.
- Knowledge retention was maintained four weeks after the initial training.
- Students and facilitators reported improved diagnostic accuracy and conceptual understanding.

## Abstract

Background

The inclusion of early clinical exposure (ECE) in the medical curriculum has emphasized the importance of developing laboratory interpretation skills among MBBS students. Clinical biochemistry, a critical component of evidence-based medicine, promotes students’ understanding of clinical issues. This study examined the impact of biochemical report interpretation as a pedagogical technique for first-year medical students, focusing on hepatobiliary function tests. It analyzes the short- and long-term retention of knowledge and assesses students' perceptions of this method.

Methods

A single-group, pre-test/post-test quasi-experimental study with a delayed post-test was conducted. Group-based learning was conducted with 120 students following a didactic presentation on hepatobiliary function tests. Assessments were conducted via a pre-test, post-test, and delayed post-test four weeks later using a structured questionnaire with multiple-choice and short-answer questions. Students created retrospective case narratives based on five laboratory results. Data analysis included statistical comparisons of the scores and input from students and facilitators.

Results

Post-test scores showed significant improvement in students' interpretation skills, particularly in recognizing obstructive jaundice. The delayed post-test scores revealed satisfactory long-term retention. Feedback highlighted the impact of this strategy in promoting conceptual understanding and improving diagnostic accuracy.

Conclusions

Retrospective case construction significantly improved hepatobiliary function test interpretation skills in first-year medical students, with immediate post-test gains sustained at four weeks.

## Linked entities

- **Diseases:** obstructive jaundice (MONDO:0006874)

## Full-text entities

- **Diseases:** obstructive jaundice (MESH:D041781)

## Full text

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC13013085/full.md

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Source: https://tomesphere.com/paper/PMC13013085