# Summary of the best evidence for non-pharmacological interventions for dyslipidemia in patients with coronary heart disease

**Authors:** Zhi Zeng, Xin Zhou, Li Jiang, Yuan Huang, Xiaochun He, Huaili Luo

PMC · DOI: 10.3389/fcvm.2026.1753853 · Frontiers in Cardiovascular Medicine · 2026-03-11

## TL;DR

This study summarizes the best evidence for non-drug treatments to manage high cholesterol in heart disease patients, helping doctors create personalized care plans.

## Contribution

A comprehensive synthesis of non-pharmacological evidence for dyslipidemia management in coronary heart disease patients.

## Key findings

- 31 studies were included, covering seven evidence themes for non-pharmacological interventions.
- Findings support lifestyle changes, TCM, and multidisciplinary approaches for managing dyslipidemia.
- The evidence can guide healthcare professionals in developing personalized intervention plans.

## Abstract

Retrieve, evaluate, and summarize evidence from domestic and international sources regarding non-pharmacological interventions for dyslipidemia in patients with coronary heart disease (CHD), providing reference for clinical practice.

Following the “6S” evidence pyramid model, a systematic search was conducted for literature on non-pharmacological interventions for dyslipidemia in CHD patients, both domestically and internationally, covering the period from January 2014 to December 2025. Two researchers independently screened and evaluated the studies for inclusion, after which the evidence was synthesized.

A total of 31 studies were ultimately included, comprising 15 English-language publications and 16 Chinese-language publications. Thirty-one evidence points were summarized, covering seven evidence themes: multidisciplinary team formation, assessment, lipid-lowering targets, lifestyle modification, non-pharmacological traditional Chinese medicine (TCM) interventions, health education, and follow-up management.

This study provides a comprehensive summary of the best available evidence on non-pharmacological interventions for dyslipidemia in patients with CHD. The findings can serve as a valuable reference for clinical practitioners, enabling healthcare professionals to develop personalized intervention plans based on the lipid profiles and specific needs of CHD patients.

## Linked entities

- **Diseases:** dyslipidemia (MONDO:0002525), coronary heart disease (MONDO:0005010)

## Full-text entities

- **Diseases:** CHD (MESH:D003327), dyslipidemia (MESH:D050171)
- **Chemicals:** lipid (MESH:D008055)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC13013076/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC13013076/full.md

## References

81 references — full list in the complete paper: https://tomesphere.com/paper/PMC13013076/full.md

---
Source: https://tomesphere.com/paper/PMC13013076