# How would Marie Kondo design a protocol? In favor of subtractive change in clinical trials

**Authors:** Rachel Bender Ignacio, Kathryn Rowan, Deborah Cook

PMC · DOI: 10.3389/fmed.2026.1776929 · Frontiers in Medicine · 2026-03-11

## Full-text entities

- **Diseases:** thrombus (MESH:D013927), myocardial infarctions (MESH:D009203), COVID-19 (MESH:D000086382), Cancer (MESH:D009369), infections (MESH:D007239), ICH (MESH:D000082122)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC13013008/full.md

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Source: https://tomesphere.com/paper/PMC13013008