# Root-localized aortic dissection in Loeys–Dietz syndrome diagnosed with the coronary computed tomography angiography: a case report

**Authors:** Ikumi Inoue, Shunsuke Inoguchi, Yasushi Ino, Keizo Kimura, Atsushi Tanaka

PMC · DOI: 10.1093/ehjcr/ytag178 · European Heart Journal. Case Reports · 2026-03-10

## TL;DR

A rare case of aortic dissection in a patient with Loeys–Dietz syndrome was diagnosed using cardiac-gated CT after initial scans were inconclusive.

## Contribution

Demonstrates the utility of cardiac-gated CT in diagnosing root-localized aortic dissection when conventional imaging is insufficient.

## Key findings

- Conventional CT failed to show dissection due to motion artifacts.
- Cardiac-gated CT provided a definitive diagnosis of root-localized aortic dissection.
- The case highlights distinct clinical features of root-localized dissection compared to type A dissection.

## Abstract

Aortic dissection is caused by a tear in the inner layer of the aorta, and blood comes between the layers of the aortic wall. Contrast-enhanced computed tomography (CT) is typically considered to be useful in its diagnosis. However, in cases of aortic dissection localized to the aortic root, diagnosis with CT or echocardiography can be challenging.

We report the case of a patient with root-localized aortic dissection that presented with acute aortic valve regurgitation. Contrast-enhanced chest CT revealed marked dilation of the aortic root, but it did not show evidence of dissection. However, there was a marked dilation of the aortic root and acute aortic regurgitation, which suggested root-localized dissection. Conventional CT was limited by motion artefacts and did not demonstrate dissection, so we decided to perform cardiac-gated CT to achieve a more accurate evaluation of the aortic root. This allowed us to make a definite diagnosis and proceed to life-saving surgery.

Acute type A-localized aortic dissection has several clinical features that were distinct from acute type A aortic dissection, which we summarize with prior cases. We found cardiac-gated CT to be useful in making definite diagnosis in this case.

## Linked entities

- **Diseases:** Loeys–Dietz syndrome (MONDO:0018954)

## Full-text entities

- **Diseases:** aortic regurgitation (MESH:D001022), Root (MESH:D011843), dilation of the aortic root (MESH:D000094628), Loeys-Dietz syndrome (MESH:D055947), Aortic dissection (MESH:D000784)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13012216/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC13012216/full.md

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Source: https://tomesphere.com/paper/PMC13012216