# Animal organoids as transformative platforms for viral infections and zoonotic cross-species viral research

## TL;DR

Animal organoids are important for studying zoonotic viruses and improving disease preparedness by enabling species-specific research.

## Contribution

The paper highlights the underutilized potential of animal organoids in veterinary virology and zoonotic research.

## Key findings

- Animal organoids replicate native tissue architecture for comparative viral infection studies.
- They enable species-specific investigations into host responses to viruses.
- Animal organoids can strengthen strategies for zoonotic disease preparedness.

## Abstract

Organoids have revolutionized human biomedical research since their development in 2010. However, as nearly 75% of human infectious diseases originate in animals, animal-derived organoids are essential to complement human models, yet their development in veterinary contexts remains scarce. Organoids replicate native tissue architecture, enabling species-specific and comparative studies of viral infection and host response. Thus, animal organoids represent a powerful field in organoid technology, advancing cross-species virology research and strengthening strategies for zoonotic disease preparedness.