# The Novel HLA Class II Alleles DRB1*15:03:06, DQB1*03:01:69 and DPB1*04:01:95 Identified in Brazilian Donors

**Authors:** Augusto Cesar Soares dos Santos Júnior, Cintia Keilla Fabreti de Oliveira, Marcelo Iraja Mion, Lucas Rafael da Silva, Raquel Aparecida Fabreti‐Oliveira

PMC · DOI: 10.1111/tan.70680 · 2026-03-24

## TL;DR

This paper reports the discovery of three new HLA class II alleles in Brazilian donors.

## Contribution

The study identifies three novel HLA alleles in the Brazilian population.

## Key findings

- The DRB1*15:03:06 allele was identified in a Brazilian donor.
- The DQB1*03:01:69 allele was found in a Brazilian donor.
- The DPB1*04:01:95 allele was detected in a Brazilian donor.

## Abstract

Identification of the novel HLA alleles DRB1*15:03:06, DQB1*03:01:69 and DPB1*04:01:95 in Brazilian individuals.

## Linked entities

- **Genes:** HLA-DRB1 (major histocompatibility complex, class II, DR beta 1) [NCBI Gene 3123], BOLA-DQB1 (MHC class II antigen) [NCBI Gene 539241], HLA-DPB1 (major histocompatibility complex, class II, DP beta 1) [NCBI Gene 3115]

## Full-text entities

- **Genes:** HLA-DRB1 (major histocompatibility complex, class II, DR beta 1) [NCBI Gene 3123] {aka DRB1, HLA-DR1B, HLA-DRB, SS1}, HLA-DQB1 (major histocompatibility complex, class II, DQ beta 1) [NCBI Gene 3119] {aka CELIAC1, HLA-DQB, IDDM1}, HLA-DPB1 (major histocompatibility complex, class II, DP beta 1) [NCBI Gene 3115] {aka DPB1, HLA-DP, HLA-DP1B, HLA-DPB}, HLA-A (major histocompatibility complex, class I, A) [NCBI Gene 3105] {aka HLAA}

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Source: https://tomesphere.com/paper/PMC13010217