# Knowledge, attitudes, and practices regarding constipation among patients with type 2 diabetes mellitus: a structural equation modeling analysis

**Authors:** Qi Wang, Jin He, Dongzhi Zhang, Jing Yu, Min Tian, Qi Zhang, Sheng Zhou, Min Meng

PMC · DOI: 10.3389/fpubh.2026.1728483 · Frontiers in Public Health · 2026-03-10

## TL;DR

This study explores how patients with type 2 diabetes understand and manage constipation, finding a gap between their knowledge and actual practices.

## Contribution

The study introduces a structural equation modeling approach to analyze the interplay between knowledge, attitudes, and practices regarding constipation in T2DM patients.

## Key findings

- Patients with T2DM have insufficient knowledge about constipation despite generally positive attitudes.
- Knowledge directly influences attitudes and practices, while attitudes also directly affect practices.
- There is a significant knowledge-practice gap, indicating a need for targeted educational interventions.

## Abstract

The present study aims to evaluate the knowledge, attitudes, and practices (KAP) related to constipation among patients diagnosed with type 2 diabetes mellitus (T2DM).

This cross-sectional study was conducted at Gansu Provincial Hospital between October 2024 and May 2025. It aimed to assess the KAP regarding constipation among patients with type 2 diabetes mellitus through a questionnaire. Furthermore, structural equation modeling (SEM) was employed to analyze the relationships among the different KAP components.

A total of 364 complete and valid questionnaires were included in the final analysis. The median age of the patients was 55 (47, 62) years, with 64.3% being male, and 41.2% having attained at least an associate's or bachelor's degree. The median (interquartile range) scores for knowledge, attitude, and practice were 6 (3.25, 9), 37 (35, 42), and 30 (27, 33), respectively (possible ranges: 0–15, 10–50, and 10–50). SEM results revealed that knowledge had a direct effect on both attitudes (β = 0.298, P = 0.004) and practices (β = 0.235, P = 0.019). Attitudes also had a direct effect on practices (β = −0.188, P = 0.009). Furthermore, knowledge indirectly influenced practices through attitudes (β = −0.056, P = 0.005).

Patients diagnosed with T2DM generally exhibited insufficient knowledge of constipation. Although they typically held positive attitudes, there was a considerable lack in their self-management practices for constipation, highlighting a significant knowledge-practice gap. This study suggests that healthcare providers should prioritize implementing targeted, evidence-based educational interventions to enhance patients' knowledge and translate positive attitudes into effective self-care behaviors.

## Linked entities

- **Diseases:** type 2 diabetes mellitus (MONDO:0005148), constipation (MONDO:0002203)

## Full-text entities

- **Diseases:** T2DM (MESH:D003924), constipation (MESH:D003248)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC13008887/full.md

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Source: https://tomesphere.com/paper/PMC13008887