# ICF rehabilitation set responsiveness after total knee arthroplasty: a retrospective study

**Authors:** Dong Wang, Long Xu, Xin Wang, Yujiao He, Jinlong Cui, Shuhua Zhou, Yin Tong, Feng Gao, Huijun Du, Wei Fan

PMC · DOI: 10.3389/fresc.2026.1784781 · Frontiers in Rehabilitation Sciences · 2026-03-10

## TL;DR

This study evaluates how well the ICF rehabilitation set tracks improvements after knee replacement surgery, finding it effective for most areas but not for joint mobility.

## Contribution

The study demonstrates the responsiveness of the ICF-RS in post-TKA rehabilitation and identifies limitations in capturing joint-specific improvements.

## Key findings

- 23 of 30 ICF-RS categories showed statistically significant improvement after rehabilitation.
- Mobility, self-care, and pain domains showed consistent directional improvement.
- The b710 category (joint mobility) showed no responsiveness despite expected clinical improvements.

## Abstract

The International Classification of Functioning, Disability and Health—Rehabilitation Set (ICF-RS) is a standardized tool for multidimensional rehabilitation assessment, but its responsiveness in post-total knee arthroplasty (TKA) inpatient settings remains underexplored.

A retrospective single-center cohort study was conducted on 47 patients who underwent primary unilateral TKA and received inpatient rehabilitation in Changsha, China (January 2023–December 2024). ICF-RS scores (30 categories) were assessed at admission and discharge. Responsiveness was evaluated using Wilcoxon signed-rank tests with Benjamini-Hochberg FDR correction. Response counts (improved/stable/worsened) were the primary outcome presentation.

Of 30 ICF-RS categories, 27 showed 100% data completeness; 3 social/sexual items had substantial missingness. Following rehabilitation, 23 categories demonstrated statistically significant improvement after FDR correction. Consistent directional improvement was observed in mobility (d450 Walking: 24/47 improved), self-care (d510–d540), and pain (b280: 26/47 improved) domains. The total score decreased from 47.51 ± 13.59 to 35.81 ± 11.38 (Cohen's d = 1.51). Notably, b710 (joint mobility) showed no responsiveness (0/47 improved, 1/47 worsened), despite expected clinical range-of-motion gains.

ICF-RS demonstrates responsiveness to post-TKA inpatient rehabilitation for most functional domains. The lack of change in b710 highlights a limitation of generic assessment tools for capturing localized physical impairments in single-joint conditions, suggesting the need for complementary condition-specific measures. The study context—where ICF-RS scores influence reimbursement—underscores the importance of assessment integrity considerations in function-based payment implementations.

## Full-text entities

- **Diseases:** pain (MESH:D010146), physical impairments (MESH:D059445)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC13008864/full.md

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Source: https://tomesphere.com/paper/PMC13008864