# Unexpected recovery of COVID-19 related Pediatric acute liver failure in a patient with an immunosuppressive syndrome with conservative management

## TL;DR

A young child with a rare immune disorder and severe liver failure from COVID-19 recovered without a transplant through early treatment.

## Contribution

This is the first reported case of Pediatric acute liver failure in Sanjad-Sakkati Syndrome successfully managed conservatively.

## Key findings

- Early aggressive treatment of severe viral infection manifestations can lead to favorable outcomes in SSS patients.
- The patient recovered from acute liver failure and MIS-C without needing a liver transplant.
- The case highlights the importance of timely intervention in managing immunosuppressive conditions.

## Abstract

Background: We describe the first pediatric case of a 20-month-old female with Sanjad-Sakkati Syndrome who developed acute liver failure with associated multisystem inflammatory syndrome in children [МІS-C] and a good outcome. The primary finding in this case, is that despite the high morbidity and mortality rates of SSS patients due to its immunosuppressive effects, early aggressive approach to treating severe viral infections manifestations, for instance acute liver failure could lead to a favourable outcome and avoid the need for liver transplant.