# Pheochromocytoma Crisis Presenting as Cardiac Arrest and Reversible Cardiomyopathy in a Young Adult: A Case Report

**Authors:** Eugeniu Gisca, Rui B Dias, Catia R Santos, Luís Val-Flores, Ana Araújo

PMC · DOI: 10.7759/cureus.104024 · Cureus · 2026-02-21

## TL;DR

A young man experienced cardiac arrest and heart failure due to a rare adrenal tumor, which was later treated and reversed with intensive care and surgery.

## Contribution

This case report highlights pheochromocytoma crisis as a reversible cause of cardiac arrest in young adults.

## Key findings

- A 32-year-old man presented with cardiac arrest and severe heart dysfunction due to a pheochromocytoma.
- Myocardial function improved after targeted treatment, confirming catecholamine-induced cardiomyopathy.
- Early diagnosis and coordinated care are essential for managing this rare but treatable condition.

## Abstract

Acute circulatory collapse and severe myocardial dysfunction in young adults without prior cardiovascular disease represent a critical diagnostic challenge in emergency and intensive care settings. We report the case of a 32-year-old man who presented to the emergency department with acute respiratory failure, profound metabolic acidosis, and hemodynamic instability, rapidly progressing to cardiac arrest with the return of spontaneous circulation. Initial evaluation revealed severe biventricular dysfunction and markedly elevated cardiac biomarkers. CT identified a large right adrenal mass suggestive of pheochromocytoma. Biochemical testing later confirmed markedly elevated plasma and urinary catecholamines and metanephrines. The patient required invasive mechanical ventilation, vasoactive support, and advanced intensive care management. Progressive recovery of myocardial function was observed following stabilization and targeted medical therapy, supporting the diagnosis of catecholamine-induced cardiomyopathy. He was subsequently referred for endocrine follow-up and definitive surgical management. This case highlights pheochromocytoma crisis as a rare but reversible cause of cardiac arrest and acute cardiomyopathy in young adults. Early recognition and coordinated intensive care and endocrine management are crucial to improve outcomes in this potentially fatal condition.

## Linked entities

- **Diseases:** pheochromocytoma (MONDO:0004974), cardiac arrest (MONDO:0000745), cardiomyopathy (MONDO:0004994), metabolic acidosis (MONDO:0000440)

## Full-text entities

- **Diseases:** circulatory collapse (MESH:D012769), metabolic acidosis (MESH:D000138), biventricular dysfunction (MESH:D018754), myocardial dysfunction (MESH:D006331), cardiovascular disease (MESH:D002318), Pheochromocytoma Crisis (MESH:D010673), Cardiac Arrest (MESH:D006323), respiratory failure (MESH:D012131), Cardiomyopathy (MESH:D009202)
- **Chemicals:** catecholamine (MESH:D002395), metanephrines (MESH:D008676)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13007818/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC13007818/full.md

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Source: https://tomesphere.com/paper/PMC13007818