# [Expression of Concern] Dexmedetomidine protects against sepsis-associated encephalopathy through Hsp90/AKT signaling

**Authors:** Lijun Yin, Xuejun Chen, Hongbo Ji, Shunli Gao

PMC · DOI: 10.3892/mmr.2026.13843 · Molecular Medicine Reports · 2026-03-11

## Full-text entities

- **Genes:** BCL2 (BCL2 apoptosis regulator) [NCBI Gene 596] {aka Bcl-2, PPP1R50}, HSP90AA1 (heat shock protein 90 alpha family class A member 1) [NCBI Gene 3320] {aka EL52, HEL-S-65p, HSP86, HSP89A, HSP90A, HSP90N}, AKT1 (AKT serine/threonine kinase 1) [NCBI Gene 207] {aka AKT, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA}, POTEF (POTE ankyrin domain family member F) [NCBI Gene 728378] {aka A26C1B, POTE2alpha, POTEACTIN}, CASP3 (caspase 3) [NCBI Gene 836] {aka CPP32, CPP32B, SCA-1}
- **Diseases:** encephalopathy (MESH:D001927), sepsis (MESH:D018805)
- **Chemicals:** Dexmedetomidine (MESH:D020927)

## Full text

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Source: https://tomesphere.com/paper/PMC13007483