# Linking first-pass reperfusion success to proteomic markers in large and medium vessel ischemic stroke: an exploratory study **Authors:** Crhistian-Mario Oblitas, Sabela Fernández-Rodicio, Manuel Rodríguez-Yáñez, Emilio Rodríguez-Castro, Arturo Gonzalez-Quintela, Jacobo Porto-Álvarez, Javier Martínez-Fernández, Miguel Blanco, Jose Luis Taboada, Sara Martnez-Reiriz, Susana B Bravo, Carmen Pena, José Castillo, Maria Luz Alonso-Alonso, Pablo Hervella, Antonio J Mosqueira, Ramón Iglesias-Rey PMC · DOI: 10.1093/pcmedi/pbag008 · Precision Clinical Medicine · 2026-02-24 ## Full-text entities - **Genes:** RAB27B (RAB27B, member RAS oncogene family) [NCBI Gene 5874] {aka C25KG}, UBFD1 (ubiquitin family domain containing 1) [NCBI Gene 56061] {aka UBPH}, ATP5MF (ATP synthase membrane subunit f) [NCBI Gene 9551] {aka ATP5J2, ATP5JL}, TLN1 (talin 1) [NCBI Gene 7094] {aka ILWEQ, TLN, talin-1}, PPBP (pro-platelet basic protein) [NCBI Gene 5473] {aka B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7}, AP1G2 (adaptor related protein complex 1 subunit gamma 2) [NCBI Gene 8906] {aka G2AD}, LIN9 (lin-9 DREAM MuvB core complex component) [NCBI Gene 286826] {aka BARA, BARPsv, Lin-9, TGS, TGS2}, UBL4A (ubiquitin like 4A) [NCBI Gene 8266] {aka DX254E, DXS254E, GDX, GET5, MDY2, TMA24}, ANXA1 (annexin A1) [NCBI Gene 301] {aka ANX1, LPC1}, CLTC (clathrin heavy chain) [NCBI Gene 1213] {aka CHC, CHC17, CLH-17, CLTCL2, Hc, MRD56}, POLR2E (RNA polymerase II, I and III subunit E) [NCBI Gene 5434] {aka RPABC1, RPB5, XAP4, hRPB25, hsRPB5}, POTEF (POTE ankyrin domain family member F) [NCBI Gene 728378] {aka A26C1B, POTE2alpha, POTEACTIN}, ND5 (NADH dehydrogenase subunit 5) [NCBI Gene 4540] {aka MTND5}, HSP90AB1 (heat shock protein 90 alpha family class B member 1) [NCBI Gene 3326] {aka D6S182, HSP84, HSP90B, HSPC2, HSPCB}, LCN2 (lipocalin 2) [NCBI Gene 3934] {aka 24p3, MSFI, NGAL, p25}, IGHV3-74 (immunoglobulin heavy variable 3-74) [NCBI Gene 28408] {aka IGHV374, VH}, SNCG (synuclein gamma) [NCBI Gene 6623] {aka BCSG1, SR}, SCPEP1 (serine carboxypeptidase 1) [NCBI Gene 59342] {aka HSCP1, RISC}, ADAP1 (ArfGAP with dual PH domains 1) [NCBI Gene 11033] {aka CENTA1, GCS1L, p42IP4}, ACTN1 (actinin alpha 1) [NCBI Gene 87] {aka BDPLT15}, CALR (calreticulin) [NCBI Gene 811] {aka CALR1, CRT, HEL-S-99n, RO, SSA, cC1qR}, ATXN1 (ataxin 1) [NCBI Gene 6310] {aka ATX1, D6S504E, SCA1}, HBA1 (hemoglobin subunit alpha 1) [NCBI Gene 3039] {aka ECYT7, HBA-T3, HBH, METHBA}, FTH1 (ferritin heavy chain 1) [NCBI Gene 2495] {aka FHC, FTH, FTHL6, HFE5, NBIA9, PIG15}, HAX1 (HCLS1 associated protein X-1) [NCBI Gene 10456] {aka HCLSBP1, HS1BP1, SCN3}, ICAM2 (intercellular adhesion molecule 2) [NCBI Gene 3384] {aka CD102}, FLNA (filamin A) [NCBI Gene 2316] {aka ABP-280, ABPX, CSBS, CVD1, FGS2, FLN}, ARFIP1 (ARF interacting protein 1) [NCBI Gene 27236] {aka HSU52521}, PDIA3 (protein disulfide isomerase family A member 3) [NCBI Gene 2923] {aka ER60, ERp57, ERp60, ERp61, GRP57, GRP58}, KHNYN (KH and NYN domain containing) [NCBI Gene 23351] {aka KIAA0323}, CTSA (cathepsin A) [NCBI Gene 5476] {aka BSVD6, GLB2, GSL, NGBE, PPCA, PPGB}, ITGB3 (integrin subunit beta 3) [NCBI Gene 3690] {aka BDPLT16, BDPLT2, BDPLT24, CD61, FMAIT1, GP3A}, FANCD2 (FA complementation group D2) [NCBI Gene 2177] {aka FA-D2, FA4, FACD, FAD, FAD2, FANCD}, PPP1R13L (protein phosphatase 1 regulatory subunit 13 like) [NCBI Gene 10848] {aka ARCME, CMAEA, IASPP, NKIP1, RAI, RAI4}, S100A9 (S100 calcium binding protein A9) [NCBI Gene 6280] {aka 60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG}, GP9 (glycoprotein IX platelet) [NCBI Gene 2815] {aka CD42a, GPIX}, PLEKHG5 (pleckstrin homology and RhoGEF domain containing G5) [NCBI Gene 57449] {aka ARHGEF45, CMTRIC, DSMA4, GEF720, HMNR4, Syx}, ACTBL2 (actin beta like 2) [NCBI Gene 345651] {aka ACT}, ACTN4 (actinin alpha 4) [NCBI Gene 81] {aka ACTININ-4, FSGS, FSGS1}, HSP90B1 (heat shock protein 90 beta family member 1) [NCBI Gene 7184] {aka ECGP, GP96, GRP94, HEL-S-125m, HEL35, TRA1}, LGALS1 (galectin 1) [NCBI Gene 3956] {aka GAL1, GBP} - **Diseases:** IS (MESH:D002544), vascular remodelling (MESH:D066253), neuroinflammation (MESH:D000090862), atherosclerosis (MESH:D050197), thrombus (MESH:D013927), inflammatory (MESH:D007249), acute ischemic stroke (MESH:D000083242) - **Species:** Homo sapiens (human, species) [taxon 9606] ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC13006874/full.md ## Figures 1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC13006874/full.md ## References 9 references — full list in the complete paper: https://tomesphere.com/paper/PMC13006874/full.md --- Source: https://tomesphere.com/paper/PMC13006874