# Effect of Bariatric Surgery on Osteoarthritis‐Related Pain and Function: A Systematic Review and Meta‐Analysis

**Authors:** Mohammed Mana Mohammed Alqahtani, António Raposo, Abdullah Mohammed Saeed Alshalaan, Saeed Mohammed Saad Asiri, Jaber Salman Yazeed Alfaifi, Saleh Mohammed Saleh Alqahtani, Rawan Asad Salameh Shawabkeh, Afnan Ali Saeed Abonukhaa, Sara Ahmed Elmahadi Ahmed, Maha Hassan Ali Asiri, Mohammad Abdullah Saeed Almastoor, Ariana Saraiva, Ashwag Saleh Alsharidah, Ibrahim Yahya Al Yasin, Najim Z. Alshahrani

PMC · DOI: 10.1002/wjs.70236 · World Journal of Surgery · 2026-01-21

## TL;DR

Bariatric surgery significantly reduces osteoarthritis diagnosis and improves joint pain and function in obese patients.

## Contribution

This study provides the first comprehensive meta-analysis on bariatric surgery's impact on osteoarthritis outcomes.

## Key findings

- Bariatric surgery reduces the likelihood of osteoarthritis diagnosis by 79%.
- Significant improvements in pain and physical function were observed at 6 and 12 months post-surgery.
- High heterogeneity across studies suggests variability in outcomes and methodologies.

## Abstract

This systematic review and meta‐analysis aimed to synthesize current evidence on the effect of metabolic and bariatric surgery on osteoarthritis (OA) diagnosis, pain, stiffness, and functional outcomes.

A systematic search was conducted in PubMed/MEDLINE, Scopus, Web of Science, and the Cochrane Library for studies published between January 2000 and July 2025. Eligible studies included adult patients undergoing any form of bariatric surgery who had either a documented diagnosis of OA before and after surgery or a quantitative assessment of OA‐related symptoms using validated instruments such as the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Data were pooled using random‐effects models, and heterogeneity was assessed using the I2 statistic.

Twelve studies published between 2007 and 2024 met the inclusion criteria, encompassing 12,000 participants across prospective and retrospective cohorts. The pooled odds ratio for OA diagnosis after surgery compared with preoperative status was 0.21 (95% CI: 0.11–0.41), indicating a 79% reduction in OA likelihood. Significant improvements were observed in WOMAC pain, stiffness, and physical function scores at 6 and 12 months postoperatively, with overall pooled mean differences of −20.80 (95% CI: −32.74 to −8.86) and −17.12 (95% CI: −25.28 to −8.96), respectively. Heterogeneity was substantial across studies (I2 > 75%).

Metabolic and bariatric surgery is associated with significant reductions in osteoarthritis diagnosis and improvements in OA‐related pain and physical function. These findings suggest that surgical weight loss may provide meaningful benefits for joint health in patients with obesity.

Metabolic and bariatric surgery is associated with significant reductions in osteoarthritis diagnosis and improvements in OA‐related pain and physical function. These findings suggest that surgical weight loss may provide meaningful benefits for joint health in patients with obesity.

## Linked entities

- **Diseases:** osteoarthritis (MONDO:0005178), obesity (MONDO:0011122)

## Full-text entities

- **Diseases:** Pain (MESH:D010146), weight loss (MESH:D015431), stiffness (MESH:C566112), OA (MESH:D010003), obesity (MESH:D009765)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC13006778/full.md

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Source: https://tomesphere.com/paper/PMC13006778