# Capacity, motivation, and opportunity model-derived taxonomy of pharmacist-led interventions applicable to people self-managing cancer medication

**Authors:** Joana Ribeiro, Ramón Morillo-Verdugo, Filipa Alves da Costa

PMC · DOI: 10.3389/fpubh.2026.1772293 · Frontiers in Public Health · 2026-03-09

## TL;DR

This study creates a taxonomy of pharmacist-led interventions to support cancer patients managing their own medication, using a model originally developed for people with HIV.

## Contribution

The novel use of the CMO model to classify pharmacist interventions in cancer care and identify feasible practices.

## Key findings

- 35 interventions were deemed important by experts, but only 8 were considered feasible due to staffing and workload issues.
- The taxonomy includes interventions considered vital for patient care despite implementation challenges.
- Experts rated interventions using a Delphi survey to determine importance and feasibility.

## Abstract

With health systems facing increasing challenges, it is important to define new care models that may release some of the burden on the workforce, whilst maintaining quality and improving patient convenience. The objective of this study was to create a taxonomy of pharmacist-led interventions aimed at supporting improved health outcomes of people self-managing cancer medication.

The list was developed following a literature search conducted in Cochrane Library and MEDLINE (PubMed) databases. The Capacity, Motivation and Opportunity (CMO) model developed for people living with HIV was used as theoretical framework to organise the pharmacist-led interventions emerging from literature. A panel of experts (hospital pharmacists with experience in oncology) selected through national hospital pharmacy societies was invited to participate in a consensusseeking Delphi survey, focusing on the most important and feasible interventions.

A total of 28 experts answered and rated 39 interventions. Whilst 35 of the proposed pharmacist-led interventions were considered important (median score above 8, on a scale of 1 to 9, without disagreement among experts), only eight were considered feasible for implementation in practice. The most frequently mentioned reasons for others not to be feasible were understaffing and excessive workload. Nevertheless, there were interventions considered vital for patients’ care and hence kept in the final taxonomy.

Future hospital-based studies should incorporate this taxonomy based on the CMO model to measure pharmacists’ interventions in real clinical practice.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** cancer (MESH:D009369)
- **Species:** Human immunodeficiency virus 1 (no rank) [taxon 11676], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13006579/full.md

## References

29 references — full list in the complete paper: https://tomesphere.com/paper/PMC13006579/full.md

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Source: https://tomesphere.com/paper/PMC13006579