# Educational inequalities in gastric cancer incidence and mortality, 1996–2015: a population-based study in Quito-Ecuador

**Authors:** Wilmer Tarupi, Esther de Vries, Patricia Cueva, Carol Guarnizo-Herreño

PMC · DOI: 10.3332/ecancer.2026.2061 · ecancermedicalscience · 2026-01-19

## TL;DR

This study found that people with lower education in Quito, Ecuador, had significantly higher rates of gastric cancer and related deaths compared to those with higher education from 1996 to 2015.

## Contribution

The study provides new evidence of educational inequalities in gastric cancer outcomes in a Latin American urban population.

## Key findings

- The risk of developing gastric cancer was about double for the least educated compared to the most educated in both men and women.
- Educational disparities in gastric cancer mortality were also significant, with higher mortality rates among the less educated.
- The study observed persistent inequalities over the 20-year period, suggesting a need for targeted interventions.

## Abstract

To assess trends in educational inequalities in gastric cancer (GC) incidence and mortality in Quito, Ecuador, from 1996 to 2015.

Using data available from the population-based cancer registry of Quito, age-specific standardised incidence and mortality rates for GC were calculated by educational level and sex. Using robust Poisson regression models, rate ratios, relative index of inequality (RII) and the slope index of inequality (SII) in incidence and mortality by educational level were estimated. Joinpoint regression analysis was performed to estimate the average annual percentage change.

The risk of developing GC among the less educated was substantially greater than among the most educated in both men and women, being around double the risk in relative terms (RIIwomen =2.1; 95% CI: 1.9, 2.3; RIImen = 1.7; 95% CI: 1.5, 1.8) and representing 14–15 cases per 100,000 person-years more cases in the lowest versus the highest educational levels (SIIwomen = 14.2; 95% CI: 12.2, 16.2; SIImen = 14.5; 95% CI: 12.0, 17.1). The differences were slightly greater for mortality.

Strong educational inequalities in GC incidence and mortality rates in Quito were observed. Efforts to target specific strategies among individuals with low education may help to ameliorate socioeconomic disparities in cancer incidence and mortality.

## Linked entities

- **Diseases:** gastric cancer (MONDO:0001056)

## Full-text entities

- **Diseases:** GC (MESH:D013274), cancer (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

51 references — full list in the complete paper: https://tomesphere.com/paper/PMC13006534/full.md

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Source: https://tomesphere.com/paper/PMC13006534