# Case Report: Simultaneous presence of Sarcoptes scabiei and fungal elements in scrapings from a patient with bullous pemphigoid

**Authors:** Yifeng Ye, Wenwen Lv, Li Chai, Qiuping Li, Zehu Liu, Xiujiao Xia

PMC · DOI: 10.3389/fmed.2026.1773134 · Frontiers in Medicine · 2026-03-09

## TL;DR

A patient developed both scabies and a fungal infection after taking glucocorticoids for a skin condition.

## Contribution

This is the first documented case of concurrent crusted scabies and Candida albicans infection following glucocorticoid therapy.

## Key findings

- Glucocorticoid therapy can lead to concurrent infections like scabies and Candida.
- The patient had bullous pemphigoid treated with glucocorticoids, resulting in secondary infections.
- This case highlights the infection risks even at low glucocorticoid doses.

## Abstract

Glucocorticoids exert their therapeutic effects by broadly suppressing the activity of immune cells, thereby increasing the risk of infection. Although this risk is dose-dependent, a clinically meaningful increase in infection risk persists even at daily doses lower than 5 mg of prednisone equivalent. We herein report the first documented case of a patient who developed concurrent crusted scabies and Candida albicans infection following glucocorticoid therapy for bullous pemphigoid.

## Linked entities

- **Chemicals:** prednisone (PubChem CID 5865)
- **Diseases:** bullous pemphigoid (MONDO:0019082), scabies (MONDO:0004525)

## Full-text entities

- **Diseases:** infection (MESH:D007239), bullous pemphigoid (MESH:D010391), Candida albicans infection (MESH:D002177), Sarcoptes scabiei (MESH:D012532)
- **Chemicals:** prednisone (MESH:D011241)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13006239/full.md

## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC13006239/full.md

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Source: https://tomesphere.com/paper/PMC13006239