# Theoretically redesigning peritoneal dialysis products for sustainability: A life cycle inventory approach

**Authors:** James Larkin, Giulia Ligabue, Gaetano Alfano, Rodrigo Martínez Cadenas, Abass Fehintola, Ingeborg Steinbach, Aycan Yasar, Niccolo Morisi, Gabriele Donati, Brett Duane

PMC · DOI: 10.1177/03913988251415097 · The International Journal of Artificial Organs · 2026-02-08

## TL;DR

This paper explores redesigning peritoneal dialysis products to reduce their environmental impact using sustainable materials and processes.

## Contribution

The study introduces a life cycle inventory approach to redesign PD products, achieving significant carbon footprint reductions.

## Key findings

- Eight redesigned PD products showed carbon footprint reductions of over 40%.
- The APD machine achieved an 87% reduction in emissions due to renewable energy and packaging changes.
- Lower-impact transport and circular waste strategies were key contributors to emission savings.

## Abstract

Peritoneal dialysis (PD) is a life-sustaining treatment for end-stage kidney disease but contributes significantly to environmental degradation due to its reliance on single-use plastics, energy-intensive manufacturing and high-volume transport. Redesigning PD products for sustainability is increasingly important as healthcare systems seek to reduce their carbon footprint. In this study, ten high-use peritoneal dialysis (PD) products were redesigned using life cycle thinking. Interventions included low-carbon transport (electric vans), renewable energy and improved waste treatment (pyrolysis). Life cycle inventories (LCIs) were modelled in Open Life Cycle Assessment (OpenLCA)and modelled using cradle-to-gate carbon footprints (kg CO₂-eq) to compare redesigned and conventional versions. All redesigned products achieved carbon footprint reductions, with eight showing decreases greater than 40%. The automated PD set and 2 L dialysate bag saw reductions of 63% and 54%, respectively (saving 1.15 and 0.86 kg CO2-eq per item). The APD machine achieved the largest percentage reduction at 87%, primarily driven by the elimination of printed packaging and the use of renewable electricity. Key contributors to emissions savings across products included lower-impact transport, sustainable packaging materials and circular waste strategies. Redesigning PD products using sustainable materials and processes can deliver substantial environmental benefits without compromising functionality. These findings support evidence-based pathways for reducing emissions in kidney care through product innovation and procurement reform.

## Linked entities

- **Diseases:** end-stage kidney disease (MONDO:0004375)

## Full-text entities

- **Diseases:** end-stage kidney disease (MESH:D007676)
- **Chemicals:** carbon (MESH:D002244), CO2 (MESH:D002245)

## Full text

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## Figures

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## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC13005883/full.md

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Source: https://tomesphere.com/paper/PMC13005883