# Managing Postangiography Radial Artery Pseudoaneurysms: Systematic Review of the Published Literature

**Authors:** Haidar Hajeh, Aditya Desai, Amer Muhyieddeen, Prabhdeep Sethi, Yasin Hussain, Tanawan Riangwiwat

PMC · DOI: 10.1016/j.jscai.2026.104263 · Journal of the Society for Cardiovascular Angiography & Interventions · 2026-02-24

## TL;DR

This study reviews the management of radial artery pseudoaneurysms after coronary angiography, finding that invasive treatments are more effective than compression.

## Contribution

A systematic review of published cases provides insights into the treatment efficacy for radial artery pseudoaneurysms.

## Key findings

- Compression had a 58.5% success rate, while thrombin injection, percutaneous interventions, and surgery had 100% success rates.
- Most pseudoaneurysms developed within the first month postprocedure, with women comprising 58.3% of cases.
- Chronic anticoagulant use was reported in 58.3% of patients, with warfarin being the most common agent.

## Abstract

With the growing use of radial access in coronary angiography, rare but significant complications such as radial artery pseudoaneurysms are increasingly encountered. This arises when arterial wall disruption leads to a soft tissue hematoma with persistent communication with the arterial lumen. Literature on management remains scarce and consists of a few case reports.

We conducted a systematic review of cases describing radial artery pseudoaneurysms following coronary angiography from January 1992 to February 2025 using PubMed, Scopus, and Google Scholar. Data extracted included patient demographics, anticoagulant use, clinical presentation, pseudoaneurysm dimensions, timing of symptom onset, and treatment strategies with associated outcomes.

A total of 56 publications comprising 75 patients were analyzed. Mean age was 70.9 years, with predominance in women (58.3%), albeit statistically nonsignificant (P = .157). All patients had access site swelling, and half had pain. Most pseudoaneurysms developed within the first month postprocedure (81.6%). Chronic anticoagulant use was reported in 58.3% of patients, with warfarin being the most common agent. Four primary treatment modalities were reported: compression (n = 24), thrombin injection (n = 9), percutaneous interventions (n = 6), and surgery (n = 36). Compression was the most frequently used but least effective method, with a 58.5% success rate as compared to 100% in the other methods.

Radial artery pseudoaneurysms are rare but potentially serious complications of transradial coronary procedures. Although compression is commonly attempted, invasive treatments offer superior efficacy.

## Linked entities

- **Chemicals:** warfarin (PubChem CID 54678486)

## Full-text entities

- **Genes:** F2 (coagulation factor II, thrombin) [NCBI Gene 2147] {aka PT, RPRGL2, THPH1}
- **Diseases:** Radial Artery Pseudoaneurysms (MESH:D017541), hematoma (MESH:D006406), pain (MESH:D010146), swelling (MESH:D004487)
- **Chemicals:** warfarin (MESH:D014859)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

63 references — full list in the complete paper: https://tomesphere.com/paper/PMC13005397/full.md

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Source: https://tomesphere.com/paper/PMC13005397