# AI-Driven Mental Health Support for Caregivers of Individuals With Alzheimer Disease: Systematic Literature Review and Development of a Conceptual Framework

**Authors:** Syeda Umme Salma, Chandra Rekha Renduchintala, Isa Siddique, Evelina Sterling, Sweta Sneha, Nazmus Sakib

PMC · DOI: 10.2196/79973 · JMIR Mental Health · 2026-03-06

## TL;DR

This paper reviews existing AI-based mental health solutions and proposes a new framework tailored to support caregivers of Alzheimer's patients.

## Contribution

The paper introduces a conceptual framework with personalized features specifically for caregivers of individuals with Alzheimer disease.

## Key findings

- A systematic literature review identified 28 eligible papers on AI-driven mental health interventions.
- A conceptual framework was developed with three unique features for caregivers of Alzheimer patients.
- The framework emphasizes personalization and includes a daily routine scheduler, reward system, and educational repository.

## Abstract

Caregivers supporting individuals with Alzheimer disease and related dementias (AD/ADRD) frequently encounter prolonged emotional strain, psychological distress, and social isolation, yet their needs are largely overlooked in current technological and clinical interventions. The special routines and obligations of caregivers of individuals with AD/ADRD are frequently not well-suited to the many artificial intelligence–driven (AI-driven) mental health solutions that are currently available. This reveals a critical need for sophisticated, customized solutions created especially to help the mental health of caregivers for patients with AD/ADRD.

To address the existing limitations of personalized mental health interventions, we aimed to identify existing literature on personalized mental health interventions using AI for specific purposes and to develop a new framework for the caregivers of individuals with AD/ADRD.

We followed an iterative approach to design the new framework. First, we did a systematic literature review of current literature to identify data analysis, AI methods, and personalized interventions. Second, we focused on the underlying gaps of this research, and by synthesizing our findings from the review, we proposed a conceptual framework.

The systematic literature review identified 73 unique results, and from external sources, we found 3 unique potential papers. Of these, 28 papers were eligible for inclusion, on which we performed our analysis. Based on the findings, we developed a new conceptual framework with 3 special features that are specifically for caregivers of patients with AD/ADRD. The 3 unique features are a personalized daily routine scheduler, which will take both patients with AD/ADRD and caregiver’s information to make it personalized, a daily reward system to keep patients motivated, and an educational repository to get the bite-sized knowledge for the lesson of handling patients in an efficient manner and taking care of one’s own mental health.

The proposed framework provides a chance for caregivers to receive mental health care, which will be personalized. The framework is developed with more updated methods than existing approaches, with a lack of personalization in this sector. This framework can be implemented with a goal of personalization and explainable approaches and can undergo further iterations to ensure it is appropriate for specific purposes.

## Linked entities

- **Diseases:** Alzheimer disease (MONDO:0004975)

## Full-text entities

- **Diseases:** dementias (MESH:D003704), AD (MESH:D000544)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13005065/full.md

## References

90 references — full list in the complete paper: https://tomesphere.com/paper/PMC13005065/full.md

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Source: https://tomesphere.com/paper/PMC13005065